Preseed.com Blog

Dear Friends, A truly inspirational story of hope!  I can’t wait to hear the tales of “The Sisterhood of the Travelling Lubricant” Blessings ~ Dr. E

Dear Dr. E,  I have been having infertility issues for the past 12 years which has never been diagnosed as something specifically wrong, just “unexplained infertility.”  My darling son was born in 2004 on my third try at IVF, when I was 39 years old.  When he turned 1, my husband & I started trying for a second.  I became pregnant on my own (for the first time in my life!) but unfortunately had a miscarriage at 9 weeks.  I lost confidence that I could do it on my own again, so I started doing IVF’s once more.  After 5 rounds & 20 good embryos inserted with none of them implanting, I gave up.  I was researching adoption options for a few months & even made an appointment to see an adoption lawyer when a friend of mine told me about Preseed in November, 2008.  Two of her other friends who had spent years TTC had recently become pregnant using Preseed.  After all the money I had spent on IVF, I figured why not give this inexpensive (and MUCH more fun sounding) option a try?

I bought a package and only used two of the applicators the first month of trying, December 2008.  I didn’t even know I was pregnant until 6 weeks in because it didn’t even occur to me that it might have worked so soon!  I am now 20 weeks pregnant with a daughter and excited beyond belief.  Did I mention that I am now 44?!  It’s truly a miracle!  I gave the remainder of the first box of Preseed to a friend who’s TTC and the second box I had bought to another friend and hope that if they conceive while using it, we can call ourselves “The Sisterhood of the Travelling Lubricant”!!!
   
My husband & I cannot possibly thank you enough for your miraculous product which we are telling everyone about.  You have brought so much joy into our lives.  We’re so grateful that we heard about your product and only wish we had heard about it earlier!)  Now I want to ask my IVF doc for a refund for those 5 insanely expensive IVF’s!

With Great Appreciation, D F

P.S.  My husband is so impressed with your results, he’s dying to buy stock in your company!

Earlier this month, at the American Society of Andrology Annual Meeting in Philadelphia, PA, INGfertility presented a study titled “Prospective Study of FertilAid Vitamin in Men with Low Sperm Quality”. This was a 90-day, randomized, placebo controlled clinical trial. The “design” of the study was important as it minimizes bias and provides more meaningful information with regard to the actual benefits of the vitamin supplement. The study was open to trying-to-conceive men with abnormal sperm parameters. Individuals who qualified for study participation were randomly (by chance) assigned to take either the FertilAid for Men supplement or an identical placebo for 90 days. Sperm samples were collected by masturbation prior to starting the treatment and at the end of treatment. It is difficult to recruit participants for these types of studies because most trying-to-conceive men are not interested in having a 50:50 change of receiving a placebo.

Fourteen men completed the trial. Eight of the 14 subjects were randomized to FertilAid for Men and 6 were randomized to placebo. No significant difference existed for demographics or sperm parameters between the groups at initial analysis. In spite of the small sample size, significant improvements were found for men taking FertilAid for Men, with regards to the total number of normal-motile sperm in the ejaculate.  This is the overall number of normally shaped and swimming sperm.  Total normal-motile sperm counts, and total motile counts have been shown in several studies to have a positive predictive relationship with fertility outcomes.  Although the mechanisms are not clearly understood, antioxidant enriched vitamin supplements such as FertilAid for Men may benefit subfertile men by boosting levels of endogenous antioxidants in semen. Several studies have reported that this population of men has low semen levels of antioxidants making their sperm more susceptible to reactive oxygen species damage, including damage to sperm chromatin. 

The feedback from our presentation at the meeting was very positive. Physicians and other scientists were particularly pleased with the randomized and placebo controlled design of the study. A frequently asked question was the cost for the supplement. The monthly cost (based on prices posted on the internet) of approximately $30 was thought to be very reasonable by those who inquired.

The manufacturer of FertilAid for Men (Fairhaven Health) contracted INGfertility to design and conduct this study. INGfertility does not sell FertilAid for Men. It does, however, include rebate coupons for FertilAid in some of its Pre-Seed packages, based on Dr. E’s endorsement and recommendation of this product for couples who are trying to conceive.

For a more detailed look at this poster, please click on the image above.

Dennis Clifton, PharmD

What an incredible TTC journey for D & M!  Let’s all send them sticky baby dust thoughts and prayers!  ~~~~~ Dr. E

I am a 32 year old women and my husband is 36 years old. We have been TTC for a few months now, and have been having unprotected sex for at least 10 years. Some how I never got pregnant after all these years. It wasn’t until the past few years we started trying to conceive but nothing happened. We decided to see a fertility doctor in December 2008 and all the testing began. They did an HSG and found out that one side of my tubes was blocked. My husband’s sperm was tested normal. I was on Clomed for a few months and had no luck conceiving. I took hormone injections prescribed by the fertilty clinic. Still we didn’t conceive that month. My husband had googled fertility lube on the web and came across Pre-Seed. We read all the success stories and got all excited and felt there was still hope for us to have a baby. Once we received the Pre-Seed in the mail we tried it that month. We actually didn’t follow the instructions properly and ended up applying the Pre-Seed after ejaculation. In turn we didn’t conceive that month. Not a total surprise. Anyways, during the next cycle we used the Pre-Seed exactly as directed and applied it before having sex and NOT after. The next month my period was abnormally late, so I took a pregnancy test and found out that I was 5 weeks pregnant.

I’m now in my 8th week of pregnancy. We both truly believe that Pre-Seed is the reason why we conceived after all these years. Thank you for a great product. I just wish the fertility clincs and other doctors would have told us about Pre-Seed instead of us wasting our time and money on  hormone injections, Clomed, HSGs and other uncomfortable tests. Thank You again for a miracle product!!!  ~ Sincerely, D&M 

Last week at the American Society of Andrology Annual Meeting in Philadelphia,  a new study reported that in vitro fertilization and embryo development in an animal model, were decreased following exposure of sperm to most lubricants specifically developed for trying to conceive couples.  These studies found that only the FDA cleared (”approved”) formula used in Pre~Seed® and Pre’®  did not interfere with fertilization or development of cattle embryos over a week of culture.  Specifically, Dr. Ray Wright of Washington State University – a previous human Embryologist, incubated bull sperm with 10% concentrations of four different lubricants marketed to not harm sperm or interfere with fertility.  These lubricants included: Pré^® Lubricant (also available as Pre~Seed^®); PRE Conceive plus^TM; ConceiveEase^TM; and the Australian product FertilityCare^TM.

Following a 30 minute incubation of sperm and lubricants, sperm were placed with cow eggs and fertilization rates observed in the laboratory.  Embryos were then allowed to develop for 7 days.  This experimental design is valuable because sperm can have damage from exposure to lubricants that does not kill them, but will impact their ability to fertilize an egg and the ability of the resulting embryo to develop normally over time. 

In this study, sperm exposed to other “fertility” lubricants resulted in embryos that developed at a significantly lower rate than did embryos exposed to no lubricant or  Pre’®.  In fact, the rate of normal embryo production was reduced by 17% or more following sperm exposure to the other products.  

Although this study did not evaluate directly what happens for a couple using the fertility lubricants during intercourse, it does underscore the importance of thorough testing of sperm function before a lubricant can claim it “does not harm sperm”.  Pre’® and Pre~Seed® have been extensively tested, which you can learn more about by going to the Science section of www.preseed.com .  The tests and clinical studies we perform on Pre’^® and Pre~Seed^® have been reviewed by the FDA. The results of this testing have allowed us to receive the FIRST and currently  ONLY clearance for lubricants to be used during fertility interventions and as safe to use when trying to conceive. 

INGfertility did pay a contract fee for service to Dr. Wright’s laboratory to have the testing reported here done.  This fee structure ensured that Dr. Wright could publish the data, regardless of study outcomes.  Obviously, we were excited, but not surprised,  to see these results which further substantiate the “fertility-friendly” quality and safety of our Pre~Seed® and Pre’® formula.  You may click here to review the presented study.  I hope that you will forward this exciting new report to your trying to conceive community!

Blessings-

Dr. E